Fertility Preservation in Girls

Do doctors discuss fertility issues before they treat young patients with cancer?

BACKGROUND Many children treated for cancer are at risk of infertility, but for girls and prepubertal boys, all fertility preservation techniques remain experimental. We have assessed UK practice relating to information provision about the effects of cancer treatment on fertility and options for fertility preservation. METHODS Paediatric oncologists prospectively completed a data form for eac...

Oocyte cryopreservation for fertility preservation in postpubertal female children at risk for premature ovarian failure due to accelerated follicle loss in Turner syndrome or cancer treatments.

OBJECTIVE To preliminarily study the feasibility of oocyte cryopreservation in postpubertal girls aged between 13 and 15 years who were at risk for premature ovarian failure due to the accelerated follicle loss associated with Turner syndrome or cancer treatments. DESIGN Retrospective cohort and review of literature. SETTING Academic fertility preservation unit. PARTICIPANTS Three girls d...

Fertility Preservation for Pre-Pubertal Girls and Young Female Cancer Patients

I-12: Optimal Strategy toward Fertility Preservation: In Vivo and In Vitro Post-Thaw Options in Gamete, Embryo and Ovarian Tissue Cryostorage

Background: Oocyte, embryo and ovarian tissue cryopreservation are proposed for fertility preservation to cancer patients who hope to be mothers after getting rid of the disease. Materials and Methods: Embryo cryopreservation is not possible for unmarried single girls without sperm partner and oocyte retrieval is a long time procedure. Thus ovarian tissue cryopreservation is suggested for ferti...

I-11: Cryopreservation and Utilization of Ovarian Tissue: When, Where and How?

In women, around 10% of cancers occur in those younger than 45 years old. Although aggressive chemotherapy/radiotherapy and bone marrow transplantation can cure more than 90% of girls and young women affected by disorders requiring such treatment, the ovaries are very sensitive to cytotoxic drugs, especially to alkylating agents. Therefore, these treatments can result in premature ovarian failu...

I-26: Surgical Techniques in Tissue Transplantation for Fertility Preservation

Background Ovarian tissue cryopreservation is an option for patients who require immediate gonagonadotoxic treatment of cancers. when there is insufficient time to conduct ovulation induction This procedure can be used in patients with genetic mutations with a high risk for premature ovarian failure.This strategy is the only option for fertility preservation in prepubertal girls or in women who...